Blastocyst Culture is a versatile method of embryo culture where the embryo developed by artificial fertilisation is allowed to grow beyond the conventional three-day period. Unlike the conventional procedures of IVF where the embryo is transferred to the womb by the third day of fertilisation, blastocyst culture involves the transfer of the embryo by the fifth or sixth day.
Blastocyst culture increases the success rate of conception. This is because the blastocyst stage of embryo development is endometrial friendly and hence implantation-ready. The probability of successful implantation is higher in this case. The blastocyst stage also ensures optimal embryo selection for transfer, which contributes to an increased implantation rate.
When is Blastocyst Culture performed?
Blastocyst culture is usually done in the following patients: –
- Who is better suited for the technique based on age and cause of infertility?
- Who has failed many times at other procedures to achieve a successful pregnancy?
- Who has strong concerns regarding the risks of multiple pregnancies?
Blastocyst Culture Procedure
The procedure of blastocyst culture works on a path parallel to the normal procedure. Once egg and sperm are retrieved and fertilised in a laboratory, they are stored there for a period of 5 to 6 days. During this time blastocyst culturing occurs.
In normal cases, the endometrial thickens and creates the ideal environment for implantation by the fifth or sixth day of ovulation. In the blastocyst culture technique, the selected embryos are transferred to the womb during this period. This maximises the probability of successful implantation.
In many patients, the method of sequential transfer is adopted. These techniques require the assistance of a skilled expert and advanced infrastructure. Blastocyst culture considerably decreases the chances of multiple pregnancies. They also ensure the transfer of well-developed and quality embryos.