Nowadays infertility occurs in about 11 percent of reproductive age couples. Most of the couples will conceive with basic infertility treatments such as fertility drugs, lifestyle changes or intrauterine insemination (IUI). In other cases, the couples require some advanced infertility treatment technologies.
Advanced Infertility Treatments
Blastocyst culture: It is a technique that intends to increase pregnancy rates and at the same time minimize the risk of multiple pregnancies. In this procedure, the embryos are typically cultured for 3 days from the cleavage stage with 4 to 10 cells, before being transferred into the uterus.
Embryo transfer: It is a step with the intent to establish a pregnancy in the assisted reproduction process, in which embryos are placed into the uterus. It can be done with or without ultrasound guidance.
Laser-assisted hatching: This procedure is done if the patient turns around a history of failure for an embryo implant in the uterine wall. In this procedure assisted hatching using the laser is used to help the embryo hatch from its protective outer shell called zona pellucida, and promotes the implantation of the embryo in the uterine wall.
IMSI: This technique of higher magnification, helps to select the morphologically best sperm from the semen and injects them directly into the eggs retrieved. In this technique the sperm will be magnified 7000 times, this magnification helps to detect intra-nuclear sperm defects and chromatin compaction defects. This increases the rate of fertilization and also reduces early abortion rates.
Embryo Co-Culture: This Co-culturing technique makes use of Human Granulosa or Endometrial Cells that may secrete supplementary molecules, which helps in growing the embryos and improves the chances of embryo survival. This co-culture system is recommended for couples with repeated IVF failures in spite of good-quality embryo transfers.
Embryo Glue: Embryo glue mimics the uterine secretions made by hyaluronan which occurs naturally in your womb, fallopian tubes and ovaries. It makes secretions from these organs stickier, aiding fertilization and implantation. On the embryo transfer day, the embryos will be dipped into the ‘glue’, to enhance the implantation effect
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