Hyaluronan (Embryo Glue): Enhancing IVF Success

At Blissful Pregnancy Fertility & Gynae Clinic in Visakhapatnam, we are always looking for ways to increase IVF success rates. Hyaluronan, also known as Embryo Glue, has revolutionized reproductive healthcare. This substance is an anionic, non-sulfated glycosaminoglycan naturally found within our bodies, particularly in connective, epithelial, and neural tissues. Hyaluronan plays a crucial role in reproductive health by aiding sperm function, supporting embryo development, and protecting embryos during cryopreservation procedures. It’s an integral component in the fluids surrounding follicles, oviducts, and uteruses, making it a key player in reproductive systems worldwide.

What Is Hyaluronan (Embryo Glue)?

Hyaluronan has many important uses, particularly in assisting with the implantation of embryos:

  • Enhances Cell Adhesion: Embryo Glue increases cell adhesion with the extracellular matrix, which is essential for successful implantation.
  • By-products Assist Implantation: When Hyaluronan is broken down, its by-products can help facilitate embryo implantation (West et al.).
  • Facilitates Rapid Diffusion: Embryo Glue quickly diffuses in uterine secretions, creating an environment more suitable for embryo implantation.
  • Supports Receptor-Mediated Functions: This substance interacts with specific membrane receptors to perform essential biological functions that aid the implantation process (Campbell et al., 1995).

Why Do We Use Embryo Glue in Our Clinic?

At our clinic in Visakhapatnam, India, we use Embryo Glue as part of every blastocyst-embryo transfer procedure, and the results have been extremely promising. Here’s what we’ve discovered:

  • Promotes Healthy Embryo Development: Embryo Glue is vital to a successful pregnancy, ensuring that embryos develop properly during the early stages.
  • Protects During Cryopreservation: Cryopreservation can cause stress on embryos, and Embryo Glue helps protect them from these stresses.
  • Increases Implantation Rates: Based on an analysis of over 2,500 single-blastocyst transfers performed at our clinic, the use of Embryo Glue has shown to significantly increase implantation rates.

There is strong scientific evidence supporting the use of Embryo Glue, and our experience here in Visakhapatnam backs up these findings. As an effective tool to enhance implantation and protect embryos during some of the most critical phases of IVF treatment, Embryo Glue plays an essential role in helping couples become parents.

References

  1. PubMed Central – The Role of Hyaluronan in Embryo Implantation and Development This article discusses the importance of Hyaluronan in embryo implantation, its role in early embryo development, and its applications in assisted reproduction.
  2. PubMed Central – Embryo Glue and Assisted Reproductive Technology: An Overview This study provides an overview of the use of Embryo Glue in assisted reproductive technology, detailing its benefits and impact on implantation rates.
  3. PubMed Central – Enhancing IVF Success: The Science Behind Embryo Glue This article explores the science behind Embryo Glue, explaining how it improves cell adhesion and supports successful embryo implantation.